This episode was amusing but not really hilarious at all. A strange character called The Mother of Invention kidnaps all the great inventors from the past (Leonardo DaVinci, Thomas Edison, Johann Gutenberg, George Washington Carver, Ben Franklin, and Wheel) and plans to destroy science and steal their inventions. He/She/It seems to suffer from a invention inferiority complex.

Of course, DaVinci escapes and with the aid of The Tick and Arthur manages to foil Mother's plan. Some of the more amusing moments occur with the Mongols Mother sends after DaVinci, but that's about it.

Leonardo DaVinci

Ooh...Wiry!

The biggest subplots here are (1) What is the Mother of Invention, anyway, male or female? and (2) If the Mother of Invention invented a time machine, doesn't that count as a significant invention? At the end of the episode, Jefferson says "I wish I had invented that!"

This episode features these Superheroes:
The Tick and Arthur

This episode features these Supervillains:
The Mother of Invention

Note; there were also Mongols, Ninjas, elephants, knights, and many other mercenaries from throughout history fighting for the Mother of Invention, but I didn't think they really counted as either Supervillains or Henchmen.

Tickisms

The Tick:
So, Vince; what's it like being a genius. I mean I know you're smart and all but all that thinking…doesn't it hurt?
Vince; in the renaissance, how big were the dinosaurs?
Fashion victims, you've crashed the wrong party!
I'm Flying! I swoop! I soar! The city laps at my heels like a grateful puppy! I am the eagle king of all I survey! I am become Shiva, Destroyer of Worlds!
Someone left the cake out in the rain…
Be reasonable; you can't destroy everything! Where would you sit?
You had your little fun…now it's time to go to jail!
You know, I've heard that the smarter you are the wrinklier your brain; and your guys brains must be the wrinkliest! Oh, sure, ordinary Joes like me and Arthur here, maybe our brains are a little on the smooth side, but you don't have to be a genius to know that Evil is Bad! And Good…isn't!

Ben Franklin:
Say, Wheel, ever think of inventing the bath?
This guy's skipping without a rope!
Haven't invented lying, yet, either.

Mother of Invention:
I do the thinking around here! You just concentrate on being viscious and hairy!